The B-Sens fell behind 3-0 in the first period on Friday night but would rally with four second period goals to win their 46th game of the season.
Anton Volchenkov scored only 18 seconds into the middle period to begin the offensive outburst. Antoine Vermette scored his 28th goal of the season before Brandon Bochenski scored a pair of goals to give Binghamton the lead.
Chris Kelly scored the lone third period goal as Binghamton won 5-3 to keep their East Division lead at three points. Philadelphia has 101 points with two games remaining while the Senators have one game left and 104 points.
Ray Emery stopped 25 of 28 shots in winning his 27th game of the season; tying his AHL career high for victories.
Tickets for tomorrow night's game are sold out, but beginning at 9 a.m. Saturday the Senators will be selling tickets for the first two home playoff games to be played on April 22nd and 23rd.